Scombroid Poisoning (Fish Poisoning)

Disease Information

Scombroid poisoning is caused by an allergic reaction to high levels of histamine in improperly stored fish. Some types of fish have naturally high levels of histidine, which bacteria convert to histamine when the fish is not stored properly. 

Fish typically associated with scombroid poisoning include:

• Tuna, swordfish, marlin, mackerel, bonito, saury, mahi mahi, yellowtail amberjack, bluefish, anchovies, and sardines.

Disease Reporting

What is required?

Health Care Providers and Clinical Laboratories

Health care providers and clinical laboratories are required by law to report cases and suspect cases of scombroid to local health departments immediately, day or night.

• Health care providers: Use our secure web-based confidential reporting system – OR – use the confidential PDF reporting form.
• See How and Where to Report for more information and local health department contacts.

For Local Health Departments

• Scombroid Poisoning Investigative Guidelines (pdf)

See Also

CDC: Fish poisoning in travelers: Ciguatera and Scombroid